Month: October 2022

In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 72824-04-5, formula is C9H17BO2, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. Synthetic Route of 72824-04-5

Liu, Jiaming;Gao, Shang;Chen, Ming research published 《 Asymmetric Syntheses of (E)-δ-Hydroxymethyl-anti-homoallylic Alcohols via Highly Enantio- and Stereoselective Aldehyde Allylation with α-Borylmethyl-(E)-crotylboronate》, the research content is summarized as follows. Highly stereo- and enantioselective synthesis of (E)-δ-hydroxymethyl-anti-homoallylic alcs. (4R,5S,E)-RCH(OH)CH(CH₃)CH=CHCH₂OH (R = pentyl, 4-bromophenyl, cyclohexyl, 1-benzofuran-2-yl, etc.) was reported. Under the developed conditions, reactions between aldehydes RCHO and chiral nonracemic α-borylmethyl-(E)-crotylboronate CH₃CH=CHCH(Bpin)CH₂Bpin upon oxidative workup gave δ-hydroxymethyl-anti-homoallylic alcs. with high E-selectivities and enantioselectivities.

Synthetic Route of 72824-04-5, Allylboronic acid pinacol ester is a useful research compound. Its molecular formula is C9H17BO2 and its molecular weight is 168.04 g/mol. The purity is usually 95%.
Allylboronic acid pinacol ester is an allylation reagent that is used to produce aldehydes from ketones. It reacts with water, yielding the desired product and formaldehyde as a byproduct. The reaction proceeds through a sequence of steps, in which the boronate ester first reacts with water to form an allylboronate ion and hydrogen gas. This intermediate then reacts with potassium t-butoxide to produce the desired allyl alcohol and potassium borohydride. Finally, the palladium complex catalyst reduces the carbonyl group of the starting material, converting it into an aldehyde. Allylboronic acid pinacol ester is commercially available as a white solid, but can also be synthesized from 2-chloro-5-pinacolylborane (pinacol) in high yield using catalytic cross coupling reactions., 72824-04-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In general, the hydroxyl group makes alcohols polar. 16545-68-9, formula is C3H6O, Because of hydrogen bonding, alcohols tend to have higher boiling points than comparable hydrocarbons and ethers. Related Products of 16545-68-9

Liu, Chunliang;Steere, Luke;McGregor, Cari;Frederick, Brittany H.;Pastoor, Timothy;Zhou, Yasheen;Liu, C. Tony;Cai, Yan;Zhou, Haibo;Xu, Musheng;Wang, Jiangong;Kim, Sang Hu;Whitesell, Luke;Cowen, Leah E.;Zhang, Yong-Kang research published 《 Exploring boron applications in modern agriculture: A structure-activity relationship study of a novel series of multi-substitution benzoxaboroles for identification of potential fungicides》, the research content is summarized as follows. Several boron-containing small mols. have been approved by the US FDA to treat human diseases. We explored potential applications of boron-containing compounds in modern agriculture by pursuing multiple research and development programs. Here, we report a novel series of 36 multi-substitution benzoxaboroles (I) wherein R¹ is t-Bu, Me, Et, etc.; Z is O, SH, or N; W is O or S; R² is H; X is H or Cl; Y is H, Me, F or Cl; and R³ is H or Me; a compound class that we recently reported as targeting geranylgeranyl transferase I (GGTase I) and thereby inhibiting protein prenylation (Kim et al., 2020). These compounds were designed, synthesized, and tested against the agriculturally important fungal pathogens Mycosphaerella fijiensis and Colletotrichum sublineolum in a structure-activity relationship study. Compounds Pr (7-chloro-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)carbamate, benzyl (7-chloro-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)carbamate, 4-chlorobenzyl (7-chloro-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)carbamate, O-(4-chlorobenzyl) (7-chloro-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)carbamothioate and O-(4-fluorobenzyl) (7-chloro-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)carbamothioate were identified as active leads with excellent antifungal MIC₉₅ values in the range of 1.56-3.13 ppm against M. fijiensis and 0.78-3.13 ppm against C. sublineolum.

Related Products of 16545-68-9, Cyclopropanol is a cyclopropane in which a hydrogen atom is replaced by a hydroxy group. It is a member of cyclopropanes and an aliphatic alcohol.
Cyclopropanol is a useful research compound. Its molecular formula is C3H6O and its molecular weight is 58.08 g/mol. The purity is usually 95%.
Cyclopropanol is a cyclic organic compound that is synthesized from sodium hydroxide solution, nitrogen atoms, and carbonyl groups. Cyclopropanol has shown inhibitory effects on inflammatory bowel disease in rats. This drug also inhibits the production of hydrogen chloride and hydrochloric acid in the stomach, which can lead to ulcers. Cyclopropanol has been found to be effective against bowel diseases such as Crohn’s disease and ulcerative colitis. This drug has been shown to have strong antioxidant properties, which may be due to its ability to reduce hydroxyl radicals., 16545-68-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 72824-04-5, formula is C9H17BO2, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Related Products of 72824-04-5

Liu, Can;Shen, Ni;Shang, Rui research published 《 Photocatalytic defluoroalkylation and hydrodefluorination of trifluoromethyls using o-phosphinophenolate》, the research content is summarized as follows. Under visible light irradiation, o-phosphinophenolate functions as an easily accessible photoredox catalyst to activate trifluoromethyl groups in trifluoroacetamides, trifluoroacetates and trifluoromethyl (hetero)arenes to deliver corresponding difluoromethyl radicals. It works in relay with a thiol hydrogen atom transfer (HAT) catalyst to enable selective defluoroalkylation and hydrodefluorination. The reaction allowed for the facile synthesis of a broad scope of difluoromethylene-incorporated carbonyl and (hetero)aromatic compounds, which are valuable fluorinated intermediates of interest in the pharmaceutical industry. The ortho-diphenylphosphino substituent, which is believed to facilitate photoinduced electron transfer, plays an essential role in the redox reactivity of phenolate. In addition to trifluoromethyl groups, pentafluoroethyl groups could also be selectively defluoroalkylated.

Related Products of 72824-04-5, Allylboronic acid pinacol ester is a useful research compound. Its molecular formula is C9H17BO2 and its molecular weight is 168.04 g/mol. The purity is usually 95%.
Allylboronic acid pinacol ester is an allylation reagent that is used to produce aldehydes from ketones. It reacts with water, yielding the desired product and formaldehyde as a byproduct. The reaction proceeds through a sequence of steps, in which the boronate ester first reacts with water to form an allylboronate ion and hydrogen gas. This intermediate then reacts with potassium t-butoxide to produce the desired allyl alcohol and potassium borohydride. Finally, the palladium complex catalyst reduces the carbonyl group of the starting material, converting it into an aldehyde. Allylboronic acid pinacol ester is commercially available as a white solid, but can also be synthesized from 2-chloro-5-pinacolylborane (pinacol) in high yield using catalytic cross coupling reactions., 72824-04-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 16545-68-9, formula is C3H6O, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , SDS of cas: 16545-68-9

Liu, Bo;Lu, Chong-Dao research published 《 Asymmetric synthesis of cis-2-aminocyclopropanols by intramolecular Mannich addition of silyloxy benzyl carbanions》, the research content is summarized as follows. An efficient, highly diastereoselective method for the preparation of protected cis-2-aminocyclopropanols from N-tert-butanesulfinyl ketimines and various aryl acylsilanes is described. A tandem process for carbon-carbon bond formation via nucleophilic addition to acylsilanes, Brook rearrangement, and intramol. Mannich reaction has been developed.

16545-68-9, Cyclopropanol is a cyclopropane in which a hydrogen atom is replaced by a hydroxy group. It is a member of cyclopropanes and an aliphatic alcohol.
Cyclopropanol is a useful research compound. Its molecular formula is C3H6O and its molecular weight is 58.08 g/mol. The purity is usually 95%.
Cyclopropanol is a cyclic organic compound that is synthesized from sodium hydroxide solution, nitrogen atoms, and carbonyl groups. Cyclopropanol has shown inhibitory effects on inflammatory bowel disease in rats. This drug also inhibits the production of hydrogen chloride and hydrochloric acid in the stomach, which can lead to ulcers. Cyclopropanol has been found to be effective against bowel diseases such as Crohn’s disease and ulcerative colitis. This drug has been shown to have strong antioxidant properties, which may be due to its ability to reduce hydroxyl radicals., SDS of cas: 16545-68-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In general, the hydroxyl group makes alcohols polar. 16545-68-9, formula is C3H6O, Because of hydrogen bonding, alcohols tend to have higher boiling points than comparable hydrocarbons and ethers. Category: alcohols-buliding-blocks

Lin, Wenwei;Yang, Lei;Chai, Sergio C.;Lu, Yan;Chen, Taosheng research published 《 Development of CINPA1 analogs as novel and potent inverse agonists of constitutive androstane receptor》, the research content is summarized as follows. Constitutive androstane receptor (CAR, NR1I3) and pregnane X receptor (PXR, NR1I2) are master regulators of endobiotic and xenobiotic metabolism and disposition. Because CAR is constitutively active in certain cellular contexts, inhibiting CAR might reduce drug-induced hepatotoxicity and resensitize drug-resistant cancer cells to chemotherapeutic drugs. We recently reported a novel CAR inhibitor/inverse agonist CINPA1 (11). Here, we have obtained or designed 54 analogs of CINPA1 and used a time-resolved fluorescence resonance energy transfer (TR-FRET) assay to evaluate their CAR inhibition potency. Many of the 54 analogs showed CAR inverse agonistic activities higher than those of CINPA1, which has an IC₅₀ value of 687 nM. Among them, 72 has an IC₅₀ value of 11.7 nM, which is about 59-fold more potent than CINPA1 and over 10-fold more potent than clotrimazole (an IC₅₀ value of 126.9 nM), the most potent CAR inverse agonist in a biochem. assay previously reported by others. Docking studies provide a mol. explanation of the structure-activity relationship (SAR) observed exptl. To our knowledge, this effort is the first chem. endeavor in designing and identifying potent CAR inverse agonists based on a novel chem. scaffold, leading to 72 as the most potent CAR inverse agonist so far. The 54 chems. presented are novel and unique tools for characterizing CAR’s function, and the SAR information gained from these 54 analogs could guide future efforts to develop improved CAR inverse agonists.

16545-68-9, Cyclopropanol is a cyclopropane in which a hydrogen atom is replaced by a hydroxy group. It is a member of cyclopropanes and an aliphatic alcohol.
Cyclopropanol is a useful research compound. Its molecular formula is C3H6O and its molecular weight is 58.08 g/mol. The purity is usually 95%.
Cyclopropanol is a cyclic organic compound that is synthesized from sodium hydroxide solution, nitrogen atoms, and carbonyl groups. Cyclopropanol has shown inhibitory effects on inflammatory bowel disease in rats. This drug also inhibits the production of hydrogen chloride and hydrochloric acid in the stomach, which can lead to ulcers. Cyclopropanol has been found to be effective against bowel diseases such as Crohn’s disease and ulcerative colitis. This drug has been shown to have strong antioxidant properties, which may be due to its ability to reduce hydroxyl radicals., Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 72824-04-5, formula is C9H17BO2, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. Product Details of C9H17BO2

Liautard, Virginie;Delgado, Marine;Colin, Boris;Chabaud, Laurent;Michaud, Guillaume;Pucheault, Mathieu research published 《 In situ generation of radical initiators using amine-borane complexes for carbohalogenation of alkenes》, the research content is summarized as follows. Atom transfer radical addition of alkyl halides to alkenes was developed using a low amount of a stable initiator, amine borane complexes. Thanks to a slow hydroboration step, the overall carbohalogenation process led to good isolated yields.

Product Details of C9H17BO2, Allylboronic acid pinacol ester is a useful research compound. Its molecular formula is C9H17BO2 and its molecular weight is 168.04 g/mol. The purity is usually 95%.
Allylboronic acid pinacol ester is an allylation reagent that is used to produce aldehydes from ketones. It reacts with water, yielding the desired product and formaldehyde as a byproduct. The reaction proceeds through a sequence of steps, in which the boronate ester first reacts with water to form an allylboronate ion and hydrogen gas. This intermediate then reacts with potassium t-butoxide to produce the desired allyl alcohol and potassium borohydride. Finally, the palladium complex catalyst reduces the carbonyl group of the starting material, converting it into an aldehyde. Allylboronic acid pinacol ester is commercially available as a white solid, but can also be synthesized from 2-chloro-5-pinacolylborane (pinacol) in high yield using catalytic cross coupling reactions., 72824-04-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 527-07-1, formula is C6H11NaO7, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Application In Synthesis of 527-07-1

Liang, Shuang;Song, Hai-yan;Wang, Li-jun research published 《 Preparation and research of green compound gas phase corrosion inhibitor for carbon steel》, the research content is summarized as follows. In order to prepare a green and efficient compound gas phase corrosion inhibitor for metal anti-rust pack-aging. Sodium benzoate (C₇H₅CO₂Na), sodium gluconate (C₆H₁₁O₇Na), phytic acid (C₆H₁₈O₂₄P₆) and sodium citrate (C₆H₅Na₃O₇) were selected as compound drugs, and A3 steel and 45^# steel were used as the exptl. objects. The compound gas phase corrosion inhibitor formula with the highest corrosion inhibition rate was selected through the volatilization weight-loss test in closed space, the rapid gas phase discrimination experiment, the electrochem. experiment and the damp heat experiment The vapor phase corrosion inhibitor with the highest corrosion inhibition rate was made into vapor phase rust prevention paper, and the rust prevention effect was compared with anti-rust base paper and com-mercial vapor phase anti-rust paper. The control experiment used scanning electron microscope (SEM) and energy spec-trometer (EDS) and contact angle meter test. The quaternary compound group 11 g/L sodium benzoate+11 g/L sodium gluconate+15 g/L phytic acid+5 g/L sodium citrate had the highest corrosion inhibition rate, and the corrosion inhibition rate for A3 steel reached 94.36%. The corrosion inhibition rate of 45^# steel reached 94.47%. The A3 steel and 45^# steel protected by the anti-rust paper had a smooth surface, no corrosion, low oxygen content, and a contact angle greater than 90°, showing obvious hydrophobicity. After the screening, the gas phase corrosion inhibitor with the highest corrosion rate was finally determined as 11 g/L sodium benzoate+11 g/L sodium gluconate+15 g/L phytic acid+5 g/L sodium citrate, and the anti-rust effect of the prepared composite VCI paper is better than the anti-rust base paper of the blank control group and the com. VCI paper.

527-07-1, Sodium Gluconate is the sodium salt of gluconic acid with chelating property. Sodium gluconate chelates and forms stable complexes with various ions, preventing them from engaging in chemical reactions.
Sodium gluconate is an organic sodium salt having D-gluconate as the counterion. It has a role as a chelator. It contains a D-gluconate.
D-Gluconic acid sodium salt is a glycol ether that is used as an injection solution. It has been shown to have antibacterial efficacy against wild-type strains of bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The in vitro antimicrobial action of D-gluconic acid sodium salt was found to be due to its ability to inhibit bacterial growth by interfering with the synthesis of DNA. D-gluconic acid sodium salt also has been shown to have antihypertensive effects in rats through the inhibition of angiotensin II type 1 receptor (AT1) signaling pathway and erythrocyte proliferation. This drug also has been shown to bind benzalkonium chloride and x-ray diffraction data show that it is crystalline in nature. The analytical method for determining the concentration of D-gluconic acid sodium salt is by electrochemical impedance, Application In Synthesis of 527-07-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 527-07-1, formula is C6H11NaO7, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. Product Details of C6H11NaO7

Li, Zuyue;Sun, Zhenping;Ji, Yanliang;Yang, Haijing;Pang, Min;Ge, Haosheng;Wu, Shaofeng;Gu, Xuebin;Zhao, Lihua;He, Yuanjie;Zhang, Xiaofu research published 《 Harm, mechanism and influence factors of mould of liquid admixtures in summer》, the research content is summarized as follows. Liquid additives such as liquid polycarboxylate based water reducer and liquid lignosulfonate water reducer are generally mildewed in summer, which not only affects the use efficiency of the product, but also brings security risks. The mildew mechanism of polycarboxylate based water reducer system with sodium gluconate was explained from the prospects of microbiol. and organic chem., and the influencing factors of the mildew were analyzed. It provides a way for researchers to carry out relevant experiments, and also provides useful suggestions for producers and users of polycarboxylate based water reducer to control mildew from the very beginning.

Product Details of C6H11NaO7, Sodium Gluconate is the sodium salt of gluconic acid with chelating property. Sodium gluconate chelates and forms stable complexes with various ions, preventing them from engaging in chemical reactions.
Sodium gluconate is an organic sodium salt having D-gluconate as the counterion. It has a role as a chelator. It contains a D-gluconate.
D-Gluconic acid sodium salt is a glycol ether that is used as an injection solution. It has been shown to have antibacterial efficacy against wild-type strains of bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The in vitro antimicrobial action of D-gluconic acid sodium salt was found to be due to its ability to inhibit bacterial growth by interfering with the synthesis of DNA. D-gluconic acid sodium salt also has been shown to have antihypertensive effects in rats through the inhibition of angiotensin II type 1 receptor (AT1) signaling pathway and erythrocyte proliferation. This drug also has been shown to bind benzalkonium chloride and x-ray diffraction data show that it is crystalline in nature. The analytical method for determining the concentration of D-gluconic acid sodium salt is by electrochemical impedance, 527-07-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In general, the hydroxyl group makes alcohols polar. 72824-04-5, formula is C9H17BO2, Because of hydrogen bonding, alcohols tend to have higher boiling points than comparable hydrocarbons and ethers. Category: alcohols-buliding-blocks

Li, Zhiyang;Li, Yichen;Li, Xingguang;Wu, Mandi;He, Ming-Liang;Sun, Jianwei research published 《 Organocatalytic asymmetric formal oxidative coupling for the construction of all-aryl quaternary stereocenters》, the research content is summarized as follows. A new catalytic asym. formal cross dehydrogenative coupling process for the construction of all-aryl quaternary stereocenters was disclosed, which provides access to rarely explored chiral tetraarylmethanes with excellent enantioselectivity. The suitable oxidation conditions and the hydrogen-bond-based organocatalysis was enabled efficient intermol. C-C bond formation in an overwhelmingly crowded environment under mild conditions. para-Quinone methides bearing an ortho-directing group serve as the key intermediate. The precise loading of DDQ was critical to the high enantioselectivity. The chiral products were also demonstrated as promising antiviral agents.

Category: alcohols-buliding-blocks, Allylboronic acid pinacol ester is a useful research compound. Its molecular formula is C9H17BO2 and its molecular weight is 168.04 g/mol. The purity is usually 95%.
Allylboronic acid pinacol ester is an allylation reagent that is used to produce aldehydes from ketones. It reacts with water, yielding the desired product and formaldehyde as a byproduct. The reaction proceeds through a sequence of steps, in which the boronate ester first reacts with water to form an allylboronate ion and hydrogen gas. This intermediate then reacts with potassium t-butoxide to produce the desired allyl alcohol and potassium borohydride. Finally, the palladium complex catalyst reduces the carbonyl group of the starting material, converting it into an aldehyde. Allylboronic acid pinacol ester is commercially available as a white solid, but can also be synthesized from 2-chloro-5-pinacolylborane (pinacol) in high yield using catalytic cross coupling reactions., 72824-04-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 647-42-7, formula is C8H5F13O, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. Formula: C8H5F13O

Li, Yuan;Di, Zhengao;Yan, Xiaoqian;Wen, Huilin;Cheng, Wei;Zhang, Jing;Yu, Ziyi research published 《 Biocatalytic living materials built by compartmentalized microorganisms in annealable granular hydrogels》, the research content is summarized as follows. The field of living materials aims to use microorganisms as cell factories for drawing energy from their environment and to modulate the performance of the materials in some manner. Although the emergence of bioprinting techniques has given rise to the creating of living materials with rationally designed properties, a challenge is the controlling of the printability of the cell-laden bioinks while maintaining the high viability of cells. Here, we present an annealable granular hydrogel system that can encapsulate and compartment microorganisms for the 3D printing of biocatalytic living materials. Yeast-laden hydrogel microparticles (HMPs) are generated by a droplet-based microfluidic preparation process and then are jammed into granular hydrogels with shear-thinning and self-recovery behaviors. Upon extrusion-based 3D printing, the jammed HMPs are able to deposit into a designated structure and can be further annealed by interparticle crosslinking. Using HMPs as microorganism carriers, yeast cells are protected by encapsulation and survive shear forces during 3D printing. Further, printed constructs display enhanced catalytic activity, which show increased ethanol production due to improved mass transfer. The combination of annealable granular hydrogels and 3D printing should enable novel routes to produce microorganisms-based living materials with further applications in bioremediation, biosensing and biomedicine.

Formula: C8H5F13O, 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol, also known as 1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol , is a useful research compound. Its molecular formula is C8H5F13O and its molecular weight is 364.1 g/mol. The purity is usually 95%.

1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol is a material used to improve nanotube composites. It is also used in the synthesis of a recyclable fluorous hydrazine carbothioate compound with NCS to catalyze the acetalization of aldehydes.

1H,1H,2H,2H-Tridecafluoro-1-n-octanol is a potent and selective halogenated hydrocarbon. It binds to DNA at the dinucleotide phosphate site, which is an important site for polymerase chain reaction (PCR) activation. 1HFN has been shown to be more effective than other halogenated hydrocarbons in vitro assays on rat liver microsomes. It has been used as an additive in wastewater treatment to remove organic contaminants and metal ions. In vivo studies have been carried out in CD-1 mice to determine the effects of 1HFN on the liver and kidneys; these studies showed no toxicological effects on these organs. 1HFN also has been shown to inhibit enzymes such as cytochrome P450 and monoamine oxidase B that are involved in drug metabolism and may lead to adverse reactions with drugs metabolized by these enzymes., 647-42-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts