Month: October 2022

Simpson, W. S. published the artcile< Photoprotection of wool fabrics by dyestuffs>, Application In Synthesis of 6054-98-4, the main research area is photodegradation prevention wool yellow dye; fading dye wool.

Photodegradation of wool fabrics was retarded by yellow dyes, presumably because their absorption spectra extend to the near-UV wavelengths. The effects of >50 dyes on the photodegradation of wool were determined by monitoring tensile strength, work-to-break, and alkali solubility Fading of a great majority of the dyes occurred as rapidly as the wool substrate was degraded. A small number of yellow dyes of the highest lightfastness gave good appearance retention of the fabric and extended its phys. useful by a factor of ≥2.

Wool Research Organisation of New Zealand Communications published new progress about Dyes. 6054-98-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H8N2Na2O6, Application In Synthesis of 6054-98-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Teng; Sun, Guangyu; Xiong, Lu; Zheng, Boying; Duan, Yaqi; Yu, Rui; Jiang, Jun; Wang, Yantao; Yang, Weiran published the artcile< Transition-metal-free decarboxylation of D-glucaric acid to furan catalyzed by SnCl4 in a biphasic system>, SDS of cas: 87-73-0, the main research area is glucaric acid decarboxylation tin chloride catalyst biphasic system.

As a useful chem., furan can be produced from bio-based chems., such as furfural and furoic acid (FA). There were few reports on the preparation of furan from bio-based C6 aldaric acids. Herein, a new method was developed to produce furan from D-glucaric acid (GA) without transition metals, and nearly 80% yield of furan was produced in the water/toluene biphasic system with SnCl4 at 200°C in 2 h. The 3-Hydroxy-2-pyrone (3-HP) and FA were proved to be the key intermediates in the formation of furan from GA, and the reaction pathway was proposed to be GA→ 3-HP→ FA→ furan based on the kinetic study, model substrate reaction, and isotope labeling experiments SnCl4 gave the highest furan yield among the common acid catalysts, and the contrast experiments suggested that H+, Cl- and Sn4+ all have promoting effect on GA conversion to furan. This method was also applicable with other C6 aldaric acids.

Molecular Catalysis published new progress about Decarboxylation. 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, SDS of cas: 87-73-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ma, Da Hun; Jaladi, Ashok Kumar; Lee, Ji Hye; Kim, Tae Sung; Shin, Won Kyu; Hwang, Hyonseok; An, Duk Keun published the artcile< Catalytic Hydroboration of Aldehydes, Ketones, and Alkenes Using Potassium Carbonate: A Small Key to Big Transformation>, Electric Literature of 403-41-8, the main research area is aldehyde ketone alkene hydroboration potassium carbonate catalyst.

An efficient transition-metal-free protocol for the hydroboration of aldehydes and ketones (reduction) was developed. The hydroboration of a wide range of aldehydes and ketones with pinacolborane (HBpin) under the K2CO3 catalyst was studied. The reaction system is practical and reliable and proceeds under extremely mild and operationally simple conditions. No prior preparation of the complex metal catalyst was required, and hydroboration occurred stoichiometrically. Further, the chemoselective reduction of aldehydes over ketones was carried out. Moreover, the authors demonstrated the use of K2CO3 as an efficient catalyst for the hydroboration of alkenes. The operational simplicity, inexpensive and transition-metal-free catalyst, and the applicability to gram-scale synthesis strengthen its potential applications for hydroboration (reduction) at an industrial scale.

ACS Omega published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Electric Literature of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ziemniak, Marcin; Pawledzio, Sylwia; Zawadzka-Kazmierczuk, Anna; Dominiak, Paulina M.; Trzybinski, Damian; Kozminski, Wiktor; Zielinski, Rafal; Fokt, Izabela; Priebe, Waldemar; Wozniak, Krzysztof; Pajak, Beata published the artcile< X-ray wavefunction refinement and comprehensive structural studies on bromo-substituted analogues of 2-deoxy-D-glucose in solid state and solution>, Quality Control of 492-62-6, the main research area is deoxyglucose conformation electron density hydrogen bond supramol self assembly.

The structural studies on two bromo-substituted derivatives of 2-deoxy-D-glucose (2-DG), namely 2-deoxy-2-bromo-D-glucose (2-BG) and 2-deoxy-2-bromo-D-mannose (2-BM) are described. 2-DG itself is an inhibitor of hexokinase, the first enzyme in the glycolysis process, playing a vital role in both cancer cell metabolism and viral replication in host cells. Because of that, 2-DG derivatives are considered as potential anti-cancer and anti-viral drugs. An X-ray quantum crystallog. approach allowed us to obtain more accurate positions of hydrogen atoms by applying Hirshfeld atom refinement, providing a better description of hydrogen bonding even in the case of data from routine X-ray experiments Obtained structures showed that the introduction of bromine at the C2 position in the pyranose ring has a minor influence on its conformation but still, it has a noticeable effect on the crystal structure. Bromine imposes the formation of a layered supramol. landscape containing hydrogen bonds, which involves the bromine atom. Periodic DFT calculations of cohesive and interaction energies (at the B3LYP level of theory) have supported these findings and highlighted energetic changes upon bromine substitution. Based on mol. wavefunction from the refinement, we calculated the electrostatic potential, Laplacian, and ELI-D, and applied them to charge-d. studies, which confirmed the geometry of hydrogen bonding and involvement of the bromine atom with these intermol. interactions. NMR studies in the solution show that both compounds do not display significant differences in their anomeric equilibrium compared to 2-DG, and the pyranose ring puckering is similar in both aqueous and solid state.

RSC Advances published new progress about Bader electron density. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Quality Control of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ding, Xiaowei; Liu, Kaihui; Yan, Qingyun; Liu, Xingyu; Chen, Ni; Wang, Guoliang; He, Shuai published the artcile< Sugar and organic acid availability modulate soil diazotroph community assembly and species co-occurrence patterns on the Tibetan Plateau>, Safety of D-Glucosaccharic acid, the main research area is sugar organic acid availability soil metabolite diazotroph community plateau; Co-occurrence network; Community assembly; Diazotrophic diversity; Sugars and organic acids.

Metabolites can mediate species interactions and the assembly of microbial communities. However, how these chems. relate to the assembly processes and co-occurrence patterns of diazotrophic assemblages in root-associated soils remains largely unknown. Here, we examined the diversity and assembly of diazotrophic communities and further deciphered their links with metabolites on Tibetan Plateau. We found that the distribution of sugars and organic acids in the root-associated soils was significantly correlated with the richness of diazotrophs. The presence of these two soil metabolites explains the variability in diazotrophic community compositions The differential concentrations of these metabolites were significantly linked with the distinctive abundances of diazotrophic taxa in same land types dominated by different plants or dissimilar soils by same plants. The assembly of diazotrophic communities is subject to deterministic ecol. processes, which are widely modulated by the variety and amount of sugars and organic acids. Organic acids, for instance, 3-(4-hydroxyphenyl)propionic acid and citric acid, were effective predictors of the characteristics of diazotrophic assemblages across desert habitats. Diazotrophic co-occurrence networks tended to be more complex and connected within different land types covered by the same plant species. The concentrations of multiple sugars and organic acids were coupled significantly with the distribution of keystone species, such as Azotobacter, Azospirillum, Bradyrhizobium, and Mesorhizobium, in the co-occurrence network. These findings provide new insights into the assembly mechanisms of root-associated diazotrophic communities across the desert ecosystems of the Tibetan Plateau.

Applied Microbiology and Biotechnology published new progress about Arenaria bryophylla. 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Safety of D-Glucosaccharic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hartogh, Danja J. Den; Tsiani, Evangelia published the artcile< Health benefits of resveratrol in kidney disease: evidence from in vitro and in vivo studies>, Safety of (E)-5-(4-Hydroxystyryl)benzene-1,3-diol, the main research area is resveratrol kidney disease health benefit review; fibroblasts; glomerulosclerosis; kidney disease; mesangial cells; renal cancer; renal epithelial cells; resveratrol.

A review. Different diseases and disorders that affect the kidneys include, but are not limited to, glomerulonephritis, diabetic nephropathy, polycystic kidney disease, kidney stones, renal fibrosis, sepsis, and renal cell carcinoma. Kidney disease tends to develop over many years, making it difficult to identify until much later when kidney function is severely impaired and undergoing kidney failure. Although conservative care, symptom management, medication, dialysis, transplantation, and aggressive renal cancer therapy are some of the current strategies/approaches to kidney disease treatment, new preventative targeted therapies are needed. Epidemiol. studies have suggested that a diet rich in fruits and vegetables is associated with health benefits including protection against kidney disease and renal cancer. Resveratrol, a polyphenol found in grapes and berries, has been reported to have antioxidant, anti-inflammatory, antidiabetic, hepatoprotective, neuroprotective, and anti-cancer properties. The current review summarizes the existing in vitro and in vivo animal and human studies examining the nephroprotective effects of resveratrol.

Nutrients published new progress about Kidney disease. 501-36-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H12O3, Safety of (E)-5-(4-Hydroxystyryl)benzene-1,3-diol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lin, Ximeng; Ji, Xiaolong; Wang, Min; Yin, Sheng; Peng, Qiang published the artcile< An alkali-extracted polysaccharide from Zizyphus jujuba cv. Muzao: Structural characterizations and antioxidant activities>, Product Details of C6H12O6, the main research area is Zizyphus fruit acidic polysaccharide antioxidant; Acidic polysaccharide; Alkaline extraction; Antioxidant activities; Structural characterization; Ziziphus jujuba cv, Muzao.

An acidic polysaccharide (SAZMP3) was isolated from jujube fruit residues by alk. extraction and purified with DEAE-Sepharose Fast Flow and Sephacryl S-300 column chromatog. The structural characterizations of SAZMP3 were determined by high-performance gelpermeation chromatog., gas chromatog., Fourier transform IR spectroscopy, methylation anal., NMR spectroscopy, SEM, and at. force microscopy. The results determined SAZMP3 was an acidic polysaccharide mainly contained rhamnose, galactose, and galacturonic acid with a mol. weight of 9.37 kDa and its backbone might mainly be composed of 1,4-α-D-GalAp with side chains of 1,3-β-D-Galp, 1,3,5-linked Araf, 1,2,4-α-L-Rhap and terminals of 1-linked Araf, 1-linked Rhap, 1-linked Galp by methylation and NMR anal. Besides, SAZMP3 has shown potential antioxidant activity in scavenging free radicals suggesting that it is an antioxidant agent, which might contribute to the functional food qualities of jujube fruit.

International Journal of Biological Macromolecules published new progress about Acidic polysaccharides Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Product Details of C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gomez, M.; Murcia, M. D.; Serrano-Arnaldos, M.; Gomez, E.; Gomez, J. L.; Hidalgo, A. M.; Maximo, M. F. published the artcile< Developing the rate equations for two enzymatic Ping-Pong reactions in series: Application to the bio-synthesis of Bis(2-ethylhexyl) azelate>, COA of Formula: C8H18O, the main research area is Bis 2 ethylhexyl azelate lipase ping pong reaction.

In this work, the rate equations of two simultaneous bisubstrate Ping-Pong in series reactions have been developed for the first time. To obtain these equations, the approximation to the stationary state has been applied and, for the total balance of enzyme, all the intermediate complexes of the two reactions, which are present simultaneously in the reaction medium, have been taken into account. To check the kinetic equations obtained, the synthesis of bis(2-ethylhexyl) azelate by transesterification from di-Et azelate and 2-ethylhexanol, in the presence of the immobilized lipase Novozym 435, has been used as reaction model. The reaction has been carried out in solvent-free conditions in a batch reactor. A design model of the reactor has also been developed and solved by applying a numerical method. The model equations have been implemented in users software in Visual Basic for Applications. In that software a routine, based on a very well-known procedure to minimize the sum of the square errors, has also been implemented. By using this software, the model parameters have been determined by fitting the exptl. data to the model. A high determination coefficient was obtained, which validated both the kinetic equations and the reactors design model.

Biochemical Engineering Journal published new progress about 104-76-7. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, COA of Formula: C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yunusoglu, Oruc published the artcile< Linalool attenuates acquisition and reinstatement and accelerates the extinction of nicotine-induced conditioned place preference in male mice>, Computed Properties of 78-70-6, the main research area is Nicotine addiction; acquisition; extinction; linalool; reinstatement.

Background: Nicotine is the addictive agent in tobacco products. The monoterpene linalool is the main ingredient in the essential oils of various aromatic plants. It has previously been demonstrated that linalool has beneficial effects on some mechanisms that are important in drug addiction. Objectives: The goal of the current study was to investigate the effect of linalool on nicotine-induced conditioned place preference (CPP) in male mice. Methods: CPP was induced by administering i.p. (i.p.) injection of nicotine (0.5 mg/kg) during the conditioning phase. The effects of nicotinic acetylcholine receptor partial agonist varenicline and linalool on the rewarding characteristics of nicotine were tested in mice with administration of linalool (12.5, 25, and 50 mg/kg, i.p.), varenicline (2 mg/kg, i.p.) or saline 30 min before nicotine injection. CPP was extinguished by repeated testing, during which conditioned mice were administered varenicline and linalool every day. One day after the last extinction trial, mice that received linalool, varenicline or saline 30 min before a priming injection of nicotine (0.1 mg/kg, i.p.) were immediately tested for reinstatement of CPP. Results: Linalool attenuated nicotine acquisition (50 mg/kg, p < .01) and reinstatement (25 and 50 mg/kg, resp. p < .05, p < .01) and accelerated the extinction of nicotine-induced CPP (50 mg/kg, p < .05). Linalool exhibited similar effects on the reference drug varenicline in the CPP phases. Conclusion: These results suggest that linalool may be helpful as an adjuvant for the treatment of nicotine use disorder. American Journal of Drug and Alcohol Abuse published new progress about 78-70-6. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Computed Properties of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jiang, Siyuan; Liu, Yufei; Zou, Xiaoyu; He, Min; Zhang, Kai; Xu, Guomin; Qin, Shuhao published the artcile< Synthesis and application of new macromolecular hindered phenol antioxidants of polyamide 6>, Product Details of C4H8O, the main research area is nylon 6 antioxidant hydroxyphenyl propionate phenylmaleimide alternting copolymer preparation.

The two macromol. antioxidants, P(3,5-di-tert-butyl-4-hydroxy cinnamic acid-N-phenylmaleimide) (PCN) and P(3-butene-1-yl-3,5-di-tert-Bu -4-hydroxyphenyl propionate-N-phenylmaleimide) (PPN) were designed and synthesized via free radical copolymerization The structures of the resulting PCN and PPN antioxidants were characterized by Fourier transform IR spectroscopy, NMR spectroscopy (1H NMR), and gel permeation chromatog. In addition, the effect of the two macromol. antioxidants on the thermal oxidation aging resistance of polyamide 6 (PA6) was studied. According to the anal. of differential scanning calorimetry, thermogravimetric anal., dynamic mech. anal., dynamic viscosity, and the mech. property of PA6 and its blends, these two types of macromol. antioxidants protected the mol. chain of PA6 from breaking, protected the crystallization of PA6 and maintained the stability of PA6 crystal form, improved the activation energy of thermal degradation and thermal stability of PA6, enhanced the strength and elasticity of PA6 and maintained the mech. properties of PA6 during aging to a certain extent.

Journal of Applied Polymer Science published new progress about Antioxidants. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Product Details of C4H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts