Month: October 2022

Formula: C8H5F13O, In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl functional group (−OH) bound to a saturated carbon atom. 647-42-7, name is 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol, An important class of alcohols, of which methanol and ethanol are the simplest examples, includes all compounds which conform to the general formula CnH2n+1OH.

Wang, Bin;Yao, Yiming;Wang, Yu;Chen, Hao;Sun, Hongwen research published 《 Per- and polyfluoroalkyl substances in outdoor and indoor dust from mainland China: contributions of unknown precursors and implications for human exposure》, the research content is summarized as follows. Per- and polyfluoroalkyl substances (PFASs) were analyzed in outdoor (n = 101) and indoor dust (n = 43, 38 paired with outdoors) samples across mainland China. From 2013 to 2017, the median concentration of ∑PFASs in outdoor dust tripled from 63 to 164 ng/g with an elevated contribution of trifluoroacetic acid and 6:2 fluorotelomer alc. In 2017, the indoor dust levels of ∑PFASs were in the range 185-913 ng/g, which were generally higher than the outdoor dust levels (105-321 ng/g). Emerging PFASs were found at high median levels of 5.7-97 ng/g in both indoor and outdoor dust samples. As first revealed by the total oxidized precursors assay, unknown perfluoroalkyl acid (PFAA)-precursors contributed 37-67 mol % to the PFAS profiles in indoor dust samples. A great proportion of C8 PFAA-precursors were precursors for perfluorooctanesulfonic acid, while C6 and C4 PFAA-precursors were mostly fluorotelomer based. Furthermore, daily perfluorooctanoic acid (PFOA) equivalent intakes of PFAAs (C4-C12) mixtures via indoor dust were first estimated at 1.3-1.5 ng/kg b.w./d for toddlers at high scenarios, which exceeds the derived daily threshold of 0.63 ng/kg b.w./d. from the European Food Safety Authority (EFSA). On this basis, an underestimation of 56%-69% likely remains without considering potential risks due to the biotransformation of unknown PFAA-precursors.

Formula: C8H5F13O, 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol, also known as 1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol , is a useful research compound. Its molecular formula is C8H5F13O and its molecular weight is 364.1 g/mol. The purity is usually 95%.

1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol is a material used to improve nanotube composites. It is also used in the synthesis of a recyclable fluorous hydrazine carbothioate compound with NCS to catalyze the acetalization of aldehydes.

1H,1H,2H,2H-Tridecafluoro-1-n-octanol is a potent and selective halogenated hydrocarbon. It binds to DNA at the dinucleotide phosphate site, which is an important site for polymerase chain reaction (PCR) activation. 1HFN has been shown to be more effective than other halogenated hydrocarbons in vitro assays on rat liver microsomes. It has been used as an additive in wastewater treatment to remove organic contaminants and metal ions. In vivo studies have been carried out in CD-1 mice to determine the effects of 1HFN on the liver and kidneys; these studies showed no toxicological effects on these organs. 1HFN also has been shown to inhibit enzymes such as cytochrome P450 and monoamine oxidase B that are involved in drug metabolism and may lead to adverse reactions with drugs metabolized by these enzymes., 647-42-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 527-07-1, formula is C6H11NaO7, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Formula: C6H11NaO7

Wang, Ben;Xu, Kaili;Wang, Yantong research published 《 Using sodium D-gluconate to suppress hydrogen production in wet aluminium waste dust collection systems》, the research content is summarized as follows. The reaction of aluminum dust and water generated in the production of aluminum products generates hydrogen, which poses a risk to wet collection systems for hydrogen explosions. In this paper, non-toxic and environmentally friendly sodium D-gluconate is used to suppress the hydrogen production reaction of aluminum waste dust and water. The results of the hydrogen evolution curves and chem. kinetics of 7 different concentrations of sodium D-gluconate showed that when the sodium D-gluconate concentration reached 0.25 g L-1, there was almost no hydrogen generation, and the rate constant was almost zero. The SEM (SEM) results showed that the surface of the reaction product became smoother with increasing solution concentration The energy dispersive spectroscopy (EDS) results showed that increasing the solution concentration slowed the formation of aluminum oxide in the product, confirming the effectiveness of sodium D-gluconate in inhibiting the reaction of aluminum waste dust particles with water. The Fourier transform IR (FTIR) results showed that sodium D-gluconate formed a chem. adsorption film on the surface of aluminum waste dust particles to prevent the dust from contacting water, thus suppressing hydrogen production This method provides a new approach to design safe wet collection systems by suppressing hydrogen production

527-07-1, Sodium Gluconate is the sodium salt of gluconic acid with chelating property. Sodium gluconate chelates and forms stable complexes with various ions, preventing them from engaging in chemical reactions.
Sodium gluconate is an organic sodium salt having D-gluconate as the counterion. It has a role as a chelator. It contains a D-gluconate.
D-Gluconic acid sodium salt is a glycol ether that is used as an injection solution. It has been shown to have antibacterial efficacy against wild-type strains of bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The in vitro antimicrobial action of D-gluconic acid sodium salt was found to be due to its ability to inhibit bacterial growth by interfering with the synthesis of DNA. D-gluconic acid sodium salt also has been shown to have antihypertensive effects in rats through the inhibition of angiotensin II type 1 receptor (AT1) signaling pathway and erythrocyte proliferation. This drug also has been shown to bind benzalkonium chloride and x-ray diffraction data show that it is crystalline in nature. The analytical method for determining the concentration of D-gluconic acid sodium salt is by electrochemical impedance, Formula: C6H11NaO7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 647-42-7, formula is C8H5F13O, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Application of C8H5F13O

Wallace, Sonjae;Lambrakos, Samuel G.;Shabaev, Andrew;Massa, Lou research published 《 On using DFT to construct an IR spectrum database for PFAS molecules》, the research content is summarized as follows. PFAS mols. are chain-linked carbon/fluorine atoms, widely distributed in the environment, and dangerously toxic biol. Here is constructed, using d. functional theory (DFT), a prototype database of IR spectra for detection of PFAS mols. Extraction of spectrum features for target mols. from measured spectra can be achieved by comparison to template spectra within a spectrum database, which are sufficient approximations of target spectra. The concept of extracting spectral features is distinct from that of inverting reflectance or transmission spectra for determination of dielec. response functions. This study continues presentation of the concept of using DFT to calculate template spectra for practical detection of target substances, by comparison with spectra within databases. Specifically, the focus here is upon PFAS mols., which include toxic and carcinogenic environmental contaminants, and whose detection based on IR spectroscopy is thus of great importance.

647-42-7, 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol, also known as 1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol , is a useful research compound. Its molecular formula is C8H5F13O and its molecular weight is 364.1 g/mol. The purity is usually 95%.

1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol is a material used to improve nanotube composites. It is also used in the synthesis of a recyclable fluorous hydrazine carbothioate compound with NCS to catalyze the acetalization of aldehydes.

1H,1H,2H,2H-Tridecafluoro-1-n-octanol is a potent and selective halogenated hydrocarbon. It binds to DNA at the dinucleotide phosphate site, which is an important site for polymerase chain reaction (PCR) activation. 1HFN has been shown to be more effective than other halogenated hydrocarbons in vitro assays on rat liver microsomes. It has been used as an additive in wastewater treatment to remove organic contaminants and metal ions. In vivo studies have been carried out in CD-1 mice to determine the effects of 1HFN on the liver and kidneys; these studies showed no toxicological effects on these organs. 1HFN also has been shown to inhibit enzymes such as cytochrome P450 and monoamine oxidase B that are involved in drug metabolism and may lead to adverse reactions with drugs metabolized by these enzymes., Application of C8H5F13O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 16545-68-9, formula is C3H6O, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , HPLC of Formula: 16545-68-9

Walker, Ann L.;Ancellin, Nicolas;Beaufils, Benjamin;Bergeal, Marylise;Binnie, Margaret;Clapham, David;Haslam, Carl P.;Holmes, Duncan S.;Hutchinson, Jonathan P.;Liddle, John;McBride, Andrew;Mirguet, Olivier;Mowat, Christopher G.;Rowland, Paul;Tiberghien, Nathalie;Trottet, Lionel;Uings, Iain;Webster, Scott P.;Zheng, Xiaozhong;Mole, Damian J. research published 《 Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis》, the research content is summarized as follows. Recently, we reported a novel role for KMO in the pathogenesis of acute pancreatitis (AP). A number of inhibitors of kynurenine 3-monooxygenase (KMO) have previously been described as potential treatments for neurodegenerative conditions and particularly for Huntington’s disease. However the inhibitors reported to date have insufficient aqueous solubility relative to their cellular potency to be compatible with the i.v. (i.v.) dosing route required in AP. We have identified and optimized a novel series of high affinity KMO inhibitors with favorable physicochem. properties. The leading example is exquisitely selective, has low clearance in two species, prevents lung and kidney damage in a rat model of acute pancreatitis and is progressing into preclin. development.

16545-68-9, Cyclopropanol is a cyclopropane in which a hydrogen atom is replaced by a hydroxy group. It is a member of cyclopropanes and an aliphatic alcohol.
Cyclopropanol is a useful research compound. Its molecular formula is C3H6O and its molecular weight is 58.08 g/mol. The purity is usually 95%.
Cyclopropanol is a cyclic organic compound that is synthesized from sodium hydroxide solution, nitrogen atoms, and carbonyl groups. Cyclopropanol has shown inhibitory effects on inflammatory bowel disease in rats. This drug also inhibits the production of hydrogen chloride and hydrochloric acid in the stomach, which can lead to ulcers. Cyclopropanol has been found to be effective against bowel diseases such as Crohn’s disease and ulcerative colitis. This drug has been shown to have strong antioxidant properties, which may be due to its ability to reduce hydroxyl radicals., HPLC of Formula: 16545-68-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Product Details of C8H15NO3, In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl functional group (−OH) bound to a saturated carbon atom. 141699-55-0, name is tert-Butyl 3-hydroxyazetidine-1-carboxylate, An important class of alcohols, of which methanol and ethanol are the simplest examples, includes all compounds which conform to the general formula CnH2n+1OH.

Wacker, Dean A.;Wang, Ying;Broekema, Matthias;Rossi, Karen;O’Connor, Steven;Hong, Zhenqiu;Wu, Ginger;Malmstrom, Sarah E.;Hung, Chen-Pin;LaMarre, Linda;Chimalakonda, Anjaneya;Zhang, Lisa;Xin, Li;Cai, Hong;Chu, Cuixia;Boehm, Stephanie;Zalaznick, Jacob;Ponticiello, Randolph;Sereda, Larisa;Han, Song-Ping;Zebo, Rachel;Zinker, Bradley;Luk, Chiuwa Emily;Wong, Richard;Everlof, Gerry;Li, Yi-Xin;Wu, Chunyu K.;Lee, Michelle;Griffen, Steven;Miller, Keith J.;Krupinski, John;Robl, Jeffrey A. research published 《 Discovery of 5-Chloro-4-((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)oxy)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyridin-2(1H)-one (BMS-903452), an Antidiabetic Clinical Candidate Targeting GPR119》, the research content is summarized as follows. G-protein-coupled receptor 119 (GPR119) is expressed predominantly in pancreatic β-cells and in enteroendocrine cells in the gastrointestinal tract. GPR119 agonists have been shown to stimulate glucose-dependent insulin release by direct action in the pancreas and to promote secretion of the incretin GLP-1 by action in the gastrointestinal tract. This dual mechanism of action has generated significant interest in the discovery of small mol. GPR119 agonists as a potential new treatment for type 2 diabetes. Herein, the authors describe the discovery and optimization of a new class of pyridone containing GPR119 agonists. The potent and selective BMS-903452 I was efficacious in both acute and chronic in vivo rodent models of diabetes. Dosing of I in a single ascending dose study in normal healthy humans showed a dose dependent increase in exposure and a trend toward increased total GLP-1 plasma levels.

141699-55-0, Tert-butyl 3-hydroxyazetidine-1-carboxylate is a useful research compound. Its molecular formula is C8H15NO3 and its molecular weight is 173.21 g/mol. The purity is usually 95%.

Tert-butyl 3-hydroxyazetidine-1-carboxylate has been shown to be a good substrate for the preparation of N-protected amino alcohols and amines by the process of reductive amination. In this synthesis, tert-butyl azetidinium chloride is used as a catalyst in the reaction with sodium hydroxide. The tert-butyl group can be removed using ammonium hydroxide in the presence of a base such as triethylamine. This reaction can be performed on a large scale, making it useful in the manufacture of pharmaceuticals. The efficiency and solubility of this process make it suitable for use as an introduction to other processes involving N-protected amino alcohols or amines., Product Details of C8H15NO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 72824-04-5, formula is C9H17BO2, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. HPLC of Formula: 72824-04-5

Vosahlo, Petr;Schulz, Jiri;Cisarova, Ivana;Stepnicka, Petr research published 《 Cyclopalladation of a ferrocene acylphosphine and the reactivity of the C-H activated products》, the research content is summarized as follows. Acylphosphines are an attractive subclass of phosphine ligands with specific reactivity and ligating properties. This study describes the synthesis of a ferrocene-based acylphosphine, FcC(O)PPh₂ (1, Fc = ferrocenyl), the corresponding phosphine chalcogenides FcC(O)P(E)Ph₂ (E = O, S and Se), and palladium(II) complexes resulting from the orthometalation of 1, viz. [Pd(μ-X)(1 – H)]₂ (2-X, where X = Cl, Br and I), which in turn serve as a convenient entry point to a range of monopalladium complexes. Thus, the cleavage of 2-X with phosphines, 4-(dimethylamino)pyridine and in situ-generated 1,3-dimesitylimidazolin-2-ylidene (L) provided complexes [PdX(L)(1 – H)] (3–5), which are typically obtained as single isomers by crystallization but undergo spontaneous isomerization in solution leading to equilibrium mixtures of cis and trans isomers. Upon treatment with sodium acetylacetonate (Na(acac)), 2-Cl was transformed into [Pd(acac)(1 – H)] (6), which reacted with (diphenylphosphino)acetic acid under proton transfer to give [Pd(Ph₂PCH₂CO₂-κ²O,P)(1 – H)] (7), while the reaction with allylating agents produced the π-allyl complex [Pd(η³-C₃H₅)(1 – H)] (9). Compound [PdCl(PMe₃)(1 – H)] was further used to prepare a series of diorganopalladium complexes [Pd(R)(PMe₃)(1 – H)] (8; R = Me, 4-C₆H₄Me, 4-C₆H₄CF₃, CH:CHC₆H₄Me-4 and CCC₆H₄Me-4). All compounds were structurally characterized using spectroscopic methods and, in most cases, also by X-ray diffraction anal. The structural data indicated the rigidity of the Pd(1 – H)⁺ fragment and revealed variations in the Pd-donor distances dictated by an interplay between the trans influence and steric demands of the ligands surrounding Pd(II). Moreover, some compounds were studied by DFT to rationalize their isomerization equilibrium and electrochem. properties, which were examined by cyclic voltammetry.

HPLC of Formula: 72824-04-5, Allylboronic acid pinacol ester is a useful research compound. Its molecular formula is C9H17BO2 and its molecular weight is 168.04 g/mol. The purity is usually 95%.
Allylboronic acid pinacol ester is an allylation reagent that is used to produce aldehydes from ketones. It reacts with water, yielding the desired product and formaldehyde as a byproduct. The reaction proceeds through a sequence of steps, in which the boronate ester first reacts with water to form an allylboronate ion and hydrogen gas. This intermediate then reacts with potassium t-butoxide to produce the desired allyl alcohol and potassium borohydride. Finally, the palladium complex catalyst reduces the carbonyl group of the starting material, converting it into an aldehyde. Allylboronic acid pinacol ester is commercially available as a white solid, but can also be synthesized from 2-chloro-5-pinacolylborane (pinacol) in high yield using catalytic cross coupling reactions., 72824-04-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 7748-36-9, formula is C3H6O2, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. Synthetic Route of 7748-36-9

Vidal, Juliana L.;Wyper, Olivia M.;MacQuarrie, Stephanie L.;Kerton, Francesca M. research published 《 Ring-Closing Metathesis of Aliphatic Ethers and Esterification of Terpene Alcohols Catalyzed by Functionalized Biochar》, the research content is summarized as follows. Functionalized biochars, renewable carbon materials prepared from waste biomass, can catalyze transformations of a range of oxygen-containing substrates via hydrogen-bonding interactions. Good conversions (up to 75.2%) to different O-heterocycles are obtained from ring-closing C-O/C-O metathesis reactions of different aliphatic ethers under optimized conditions using this heterogeneous, metal-free, and easy separable catalyst. The diversity in the sorts of O-containing feedstocks is further demonstrated by the utilization of functionalized biochar to promote the esterification of terpene alcs., an important reaction in food and flavor industries. Under the optimized conditions, full conversions to various terpene esters are obtained. Moreover, both of the reactions studied herein are performed under neat conditions, thus increasing the overall sustainability of the process described.

Synthetic Route of 7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 533-73-3, formula is C6H6O3, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Recommanded Product: Benzene-1,2,4-triol

Verma, Neha;Ananthakrishnan, Rajakumar research published 《 Boosted Charge Transfer Efficacy of an All-Solid-State Z-Scheme BiOI-CD-CdS Photocatalyst for Enhanced Degradation of 4-Nitrophenol and Oxidation of Benzyl Alcohol under Visible Light**》, the research content is summarized as follows. Recently, utilization of solar light for chem. reactions has become a popular approach. Inspired by nature, we fabricated a ternary system, BiOI-CD-CdS, which is more durable and shows multiple photocatalytic applications. The incorporated carbon dots (CD) serve as a solid-state electron mediator and Z-scheme facilitator. The material was employed for photooxidative degradation of 4-nitrophenol (a pollutant) and selective oxidation of benzyl alc. into the corresponding aldehyde in an acetonitrile medium. In this study, 10 wt % BiOI-CD-CdS (denoted as 10 wt % BCC) shows the highest photocatalytic performance compared to the individual semiconductors BiOI and CdS, and gave a degradation rate constant (k) of 12.67×10-3 min-1 (4-nitrophenol), which is 17.5 times and 6.5 times higher than its individual components. Moreover, the catalyst offers a 90 % conversion of benzyl alc. to benzaldehyde with high selectivity (98 %). Directed by mechanistic insight, the charge transfer process was observed between BiOI and CdS, where CD serves as an electron mediator/charge separator. The radicals formed by the photocatalysis are superoxide (O2.-), hydroxyl radicals (.OH), and holes (h+). The intermediates and mechanistic pathways were traced using HPLC, GC-MS, and EPR studies. Moreover, the work demonstrated a smart strategy for designing a ternary Z-scheme photocatalytic system, which could be useful for environmental decontamination and selective organic transformation under visible light.

Recommanded Product: Benzene-1,2,4-triol, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., 533-73-3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 16545-68-9, formula is C3H6O, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. HPLC of Formula: 16545-68-9

Vellakkaran, Mari;Kim, Taehwan;Hong, Sungwoo research published 《 Visible-Light-Induced C4-Selective Functionalization of Pyridinium Salts with Cyclopropanols》, the research content is summarized as follows. The site-selective C-H functionalization of heteroarenes is of considerable importance for streamlining the rapid modification of bioactive mols. A general strategy for visible-light-induced β-carbonyl alkylation at the C4 position of pyridines with high site selectivity using various cyclopropanols and N-amidopyridinium salts. In this process, hydrogen-atom transfer between the generated sulfonamidyl radicals and O-H bonds of cyclopropanols generates β-carbonyl radicals, provided efficient access to synthetically valuable β-pyridylated (aryl)ketones, aldehydes, and esters with broad functional-group tolerance. In addition, the mild method served as an effective tool for the site-selective late-stage functionalization of complex and medicinally relevant mols.

HPLC of Formula: 16545-68-9, Cyclopropanol is a cyclopropane in which a hydrogen atom is replaced by a hydroxy group. It is a member of cyclopropanes and an aliphatic alcohol.
Cyclopropanol is a useful research compound. Its molecular formula is C3H6O and its molecular weight is 58.08 g/mol. The purity is usually 95%.
Cyclopropanol is a cyclic organic compound that is synthesized from sodium hydroxide solution, nitrogen atoms, and carbonyl groups. Cyclopropanol has shown inhibitory effects on inflammatory bowel disease in rats. This drug also inhibits the production of hydrogen chloride and hydrochloric acid in the stomach, which can lead to ulcers. Cyclopropanol has been found to be effective against bowel diseases such as Crohn’s disease and ulcerative colitis. This drug has been shown to have strong antioxidant properties, which may be due to its ability to reduce hydroxyl radicals., 16545-68-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 7748-36-9, formula is C3H6O2, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Name: Oxetan-3-ol

Vandenberg, E. J.;Mullis, J. C.;Juvet, R. S. Jr.;Miller, T.;Nieman, R. A. research published 《 Poly(3-hydroxyoxetane) – an analog of poly(vinyl alcohol): synthesis, characterization, and properties》, the research content is summarized as follows. The spontaneous polymer formed from 3-hydroxyoxetane (I) is linear, low-mol.-weight, water-soluble, atactic poly(3-hydroxyoxetane) (II) of high crystallinity with -OCH₂CH(OH)CH₂OH end units. The highly crystalline nature of II may be related to the crystalline nature of atactic poly(vinyl alc.) since I can be considered a copolymer of vinyl alc. and HCHO. Spontaneous II apparently is formed in a cationic polymerization by the carboxylic acids produced by the air oxidation of I on standing at room temperature for several months. The polymerization can be duplicated by the addition of 2% hydroxyacetic acid to I. The rate of this unusual cationic polymerization increases greatly with acid strength, e.g., trifluoromethanesulfonic acid reacts explosively with pure I. A mechanism is proposed for this cationic polymerization High-mol.-weight, water-soluble, linear, atactic, and highly crystalline II (m.p. = 155°) was made by polymerizing the trimethylsilyl ether of I with the iso-Bu₃Al-0.7H₂O cationic catalyst followed by hydrolysis. Two ¹H NMR methods for measuring the tacticity of II were developed based on finding two different types of methylene units at 400 MHz with the methine protons decoupled. Also, an ¹H-NMR method was developed for measuring branching in II. High-mol.-weight, linear II with enhanced isotacticity (80%) was obtained in low yield as a water-insoluble fraction with T_m = 223°. The low-mol.-weight II prepared previously by the base-catalyzed, rearrangement polymerization of glycidol is highly branched.

7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., Name: Oxetan-3-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts