Month: October 2022

Hewitt, Kirsten A.; Xie, Pei-Pei; Thane, Taylor A.; Hirbawi, Nadia; Zhang, Shuo-Qing; Matus, Alissa C.; Lucas, Erika L.; Hong, Xin; Jarvo, Elizabeth R. published the artcile< Nickel-Catalyzed Domino Cross-Electrophile Coupling Dicarbofunctionalization Reaction To Afford Vinylcyclopropanes>, SDS of cas: 627-27-0, the main research area is vinylcyclopropane enantioselective diastereoselective preparation DFT; alkynyl tosylpiperidine domino cross electrophile coupling dicarbofunctionalization nickel catalyst.

A nickel-catalyzed domino reaction was established that harnesses sulfonamide, alkyl chloride, and alkyne functionalities in a multistep sequence to afford vinylcyclopropanes I [R = Me, n-hexyl, Ph, etc.] bearing tetrasubstituted olefins. The starting materials were prepared by iron-promoted aza-Prins reactions of ynals. This method provided rapid synthetic access to valuable building blocks with applications in medicinal chem. Exptl. and computational results supported the initiation of the catalytic cycle by the oxidative addition of propargylic sulfonamide, and a key ambiphilic allenylnickel intermediate leads to a bifurcated reaction pathway that generates olefin isomers.

ACS Catalysis published new progress about Alkenes, trans Role: SPN (Synthetic Preparation), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, SDS of cas: 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gu, Jinyan; Zhang, Haihui; Wen, Chaoting; Zhang, Jixian; He, Yuanqing; Ma, Haile; Duan, Yuqing published the artcile< Purification, characterization, antioxidant and immunological activity of polysaccharide from Sagittaria sagittifolia L.>, Related Products of 3458-28-4, the main research area is Sagittaria polysaccharide purification antioxidant immunol; Antioxidant; Immunomodulatory; Sagittaria sagittifolia L. polysaccharide.

As a healthy food and traditional Chinese medicine, sagittaria sagittifolia L. has been used for a long history. Nevertheless, reports on the bioactivity and chem. characterization of S. sagittifolia L. polysaccharides are still very rare. In this paper, ultrasound-assisted method (UAE) was used to extract S. sagittifolia L. polysaccharides, after alc. precipitation and column chromatog. isolation, the structural characteristics, antioxidant and immunol. activities of the purified polysaccharide (SPU60-W) were preliminarily investigated. The results indicated SPU60-W (16.62 kDa) was a pyranoid polysaccharide containing α-glycosidic bond composed of mannose, xylose, and glucose with a molar ratio of 2.69:2.04:95.27. It consisted of slender wormlike strands, which may involve some degree of aggregation of helixes, as well as a small proportion of irregular spherical structures. Furthermore, antioxidant activity anal. showed that SPU60-W possess excellent hydroxyl and ABTS radical scavenging activity comparable to vitamin C (Vc), and moderate DPPH radical scavenging activity. Immunity tests suggested that SPU60-W significantly promoted the proliferation, phagocytosis and NO production of mouse macrophage RAW264.7. According to this study, SPU60-W might be utilized as a potent antioxidant and immunomodulator in food and medicinal industry.

Food Research International published new progress about Antioxidants. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Related Products of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Grabka, Michal; Kula, Przemyslaw; Szala, Mateusz; Jasek, Krzysztof; Czerwinski, Michal published the artcile< Fluorophenol-Containing Hydrogen-Bond Acidic Polysiloxane for Gas Sensing-Synthesis and Characterization>, COA of Formula: C4H8O, the main research area is fluorophenol polysiloxane hydrosilylation gas sensor property; coatings for gravimetric sensors; hydrogen-bond acidic polysiloxane; on-site detection of CWAs; sensor polymer.

In this work, the synthesis of a new polysiloxane, poly {dimethylsiloxane-co-[4-(2,3-difluoro-4-hydroxyphenoxy) butyl] methylsiloxane} (dubbed PMFOS), is presented. This polymer exhibits high hydrogen bond acidity and was designed to be used as a sensor layer in gas sensors. The description of the synthetic route of the PMFOS has been divided into two main stages: the synthesis of the functional substituent 4-(but-3-en-1-yloxy)-2,3-difluorophenol, and the post-polymerization functionalization of the polysiloxane chain (methylhydrosiloxane-dimethylsiloxane copolymer) via hydrosilylation. The synthesized material was subjected to instrumental anal., which confirmed its structure. The performed thermal anal. made it possible to determine some properties important for the sensor application, such as glass transition temperature and decomposition temperature The results showed that PMFOS meets the requirements for materials intended for use in gas sensors based on acoustoelec. transducers.

Polymers (Basel, Switzerland) published new progress about Gas sensors. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, COA of Formula: C4H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fouad, Farid; Khairuddean, Melati; Twieg, Robert published the artcile< Synthesis and liquid crystalline studies of biphenylyl-1,3,4-thiadiazoles and diphenyl-1,3,4-thiadiazoles: influence of side chain semifluorination and lateral ring fluorination>, Computed Properties of 627-27-0, the main research area is biphenylyl thiadiazole preparation liquid crystal structure property thermal stability; diphenyl thiadiazole preparation liquid crystal structure property thermal stability.

Four series of 1,3,4-thiadiazole based compounds I [R = C2H5, C6H13O; R1 = Me, Et, n-Pr, etc.] II [R2 = R3 = C9H19, F(CF2)4(CH2)3, F(CF2)6(CH2)3, etc.] and III [X = Y = H, F] were synthesized, and their liquid crystalline properties were studied. Series I compounds I [R = C2H5, C6H13O; R1 = Me, Et, n-Pr, etc.] were two tailed biphenylyl-1,3,4-thiadiazoles. Series II II [R2 = R3 = C9H19, F(CF2)4(CH2)3, F(CF2)6(CH2)3, etc.] was a set of new diphenyl-1,3,4-thiadiazoles with perhydrogenated and semifluorinated tails. Series III compounds II [R2 = R3 = F(CF2)4(CH2)3, F(CF2)6(CH2)3, etc.] were sym. semifluorinated diphenyl-1,3,4-thiadiazoles. Two laterally fluorinated diphenyl-1,3,4-thiadiazoles along with their parent nonfluorinated compound III [X = Y = H, F] were also synthesized. In all of the four series SmA and/or SmC phases was observed

Liquid Crystals published new progress about Carboxylic acids Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Computed Properties of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Qi; Wang, Zi-Lu; Lu, Huan-Xuan; Xu, Yun-He published the artcile< Copper-Catalyzed Enantioselective 1,4-Protosilylation of Alkynyl-substituted Enones to Synthesize the Highly Diastereomeric Chiral Homoallenylsilanes>, Electric Literature of 10602-04-7, the main research area is copper catalyzed enantioselective protosilylation alkynyl enone; diastereomeric enantioselective chiral homoallenylsilane preparation crystal mol structure.

A copper-catalyzed 1,4-protosilylation of α-alkynyl-enones to form the functionalized chiral homoallenylsilanes was developed. In the presence of a chiral monopyridine oxazoline ligand, a variety of trisubstituted allene derivatives bearing a contiguous stereogenic center and axis were prepared in good yields with excellent enantioselectivities and diastereoselectivities.

Organic Letters published new progress about Allenes Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Electric Literature of 10602-04-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Schaarschmidt, Stephanie; Glaubitz, Ulrike; Erban, Alexander; Kopka, Joachim; Zuther, Ellen published the artcile< Differentiation of the High Night Temperature Response in Leaf Segments of Rice Cultivars with Contrasting Tolerance>, SDS of cas: 87-73-0, the main research area is Oryza cultivar leaf segment high night temperature; RNA-Seq; high night temperature; leaf segments; metabolomics; rice cultivars; sheath.

High night temperatures (HNT) affect rice yield in the field and induce chlorosis symptoms in leaves in controlled chamber experiments However, little is known about mol. changes in leaf segments under these conditions. Transcript and metabolite profiling were performed for leaf segments of six rice cultivars with different HNT sensitivity. The metabolite profile of the sheath revealed a lower metabolite abundance compared to segments of the leaf blade. Furthermore, pre-adaptation to stress under control conditions was detected in the sheath, whereas this segment was only slightly affected by HNT. No unique significant transcriptomic changes were observed in the leaf base, including the basal growth zone at HNT conditions. Instead, selected metabolites showed correlations with HNT sensitivity in the base. The middle part and the tip were most highly affected by HNT in sensitive cultivars on the transcriptomic level with higher expression of jasmonic acid signaling related genes, genes encoding enzymes involved in flavonoid metabolism and a gene encoding galactinol synthase. In addition, gene expression of expansins known to improve stress tolerance increased in tolerant and sensitive cultivars. The investigation of the different leaf segments indicated highly segment specific responses to HNT. Mol. key players for HNT sensitivity were identified.

International Journal of Molecular Sciences published new progress about Chlorosis (plant). 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, SDS of cas: 87-73-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rana, Rohit; Shreya; Upadhyay, Rahul; Maurya, Sushil K. published the artcile< Synthesis of Macrocyclic Lactones and Dilactones Using Olive Oil>, Recommanded Product: But-3-en-1-ol, the main research area is ester olive oil Grubbs second generation macrocyclization catalyst; lactone preparation; dilactone preparation.

Macrocyclic lactones have redolent characteristics of muscones that originate from the rectal musk organs of the musk deer. These lactones are the primary raw material in the flavor and fragrance industry and are also found within the cyclic frameworks of various bioactive mols. Due to great demand, many efforts have been made for their synthesis; however, strategies generating a large number of macrocyclic analogs from renewable resources have not been fully realized and are urgently required. Here, we outline a sustainable, straightforward, and eco-friendly approach to synthesize high-valued macrocyclic lactones utilizing olive oil under greener reaction conditions. The outlined method allows us to turn biomass into valuable 12- to 29-membered lactones and dilactones.

ACS Omega published new progress about Diastereoselective synthesis. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Recommanded Product: But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Alonso-Gil, Santiago published the artcile< MonteCarbo : A software to generate and dock multifunctionalized ring molecules>, SDS of cas: 492-62-6, the main research area is software multifunctionalized ring active site glycosidase; Monte Carlo; carbohydrates; conformations; docking; drug design.

MonteCarbo is an open-source software to construct simple 5-, 6-, and 7-membered ring multifunctionalized monosaccharides and nucleobases and dock them into the active site of carbohydrate-active enzymes. The core bash script executes simple orders to generate the Z-matrix of the neutral mol. of interest. After that, a Fortran90 code based on a pseudo-random number generator (Monte Carlo method) is executed to assign dihedral angles to the different rotamers present in the structure (ring and rotating functional groups). The program also has a generalized internal coordinates (GIC) implementation of the Cremer and Pople puckering coordinates ring. Once the structures are generated and optimized, a second code is ready to execute in serial the docking of multiple conformers in the active site of a wide family of enzymes.

Journal of Computational Chemistry published new progress about Computer program. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, SDS of cas: 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Prakash, Anand; Vadivel, Vellingiri published the artcile< Citral and linalool nanoemulsions: impact of synergism and ripening inhibitors on the stability and antibacterial activity against Listeria monocytogenes>, Name: 3,7-Dimethylocta-1,6-dien-3-ol, the main research area is Listeria citral linalool nanoemulsion antibacterial activity ripening inhibitor synergism; Citral; Linalool; Listeria monocytogenes; Nanoemulsions; Ripening inhibitors; Sesame oil.

The present work explored the influence of individual and combinations of citral and linalool along with different Ostwald ripening inhibitors on the nanoemulsion stability and their antibacterial activity against Listeria monocytogenes. Nine different nanoemulsions (N1-N9) containing individual or combinations of citral, linalool with or without ripening inhibitors (medium chain triglycerides, coconut oil, sesame oil and castor oil) were formulated with 5% Tween-80 using ultrasonic emulsification. N1 formulation containing 5% citral without ripening inhibitors showed the least mean droplet diameter of 20.44 nm. Addition of linalool with the citral nanoemulsions was found to have deleterious effect on the thermodn. and kinetic stabilities. Incorporation of ripening inhibitors controlled the increase of droplet size and polydispersity index in N6-N9 during the 90 days storage period, but decreased their antibacterial activity. N8 formulation containing sesame oil as ripening inhibitor was found to be the best in controlling Ostwald ripening. N1 formulation which showed the best antibacterial activity (MIC 0.312%) was found to disrupt the bacterial membrane integrity. N1 formulation also showed a promising biofilm inhibition of 83.51%. Therefore, N1 formulation containing 5% citral could be recommended as an efficient disinfectant against food-borne pathogen Listeria monoctyogenes in food industry. Moreover, addition of sesame oil in the nanoemulsion formulation of citral or linalool could increase their stability.

Journal of Food Science and Technology (New Delhi, India) published new progress about Acoustic emulsification. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Name: 3,7-Dimethylocta-1,6-dien-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Soboleva, Oxana A.; Protsenko, Pavel V.; Korolev, Vadim V.; Viktorova, Jekaterina; Yakushenko, Alexey; Kudla, Ruth; Gutmann, Jochen S.; Tsarkova, Larisa A. published the artcile< Aroma Molecules as Dynamic Volatile Surfactants: Functionality beyond the Scent>, Related Products of 78-70-6, the main research area is aroma mol dynamics surfactant volatile interfacial; dynamic surface tension; essential oils; ink-jet printing; terpens; volatile surfactants; wetting.

Understanding of nonequilibrium processes at dynamic interfaces is indispensable for advancing design and fabrication of solid-state and soft materials. The research presented here unveils specific interfacial behavior of aroma mols. and justifies their usage as multifunctional volatile surfactants. As nonconventional volatile amphiphiles, we study com. available poorly water-soluble compounds from the classes of synthetic and essential flavor oils. Their disclosed distinctive feature is a high dynamic interfacial activity, so that they decrease the surface tension of aqueous solutions on a time scale of milliseconds. Another potentially useful property of such amphiphiles is their volatility, so that they notably evaporate from interfaces on a time scale of seconds. This behavior allows for control of wetting and spreading processes. A revealed synergetic interfacial behavior of mixtures of conventional and volatile surfactants is attributed to a decrease of the activation barrier as a result of high statistical availability of new sites at the surface upon evaporation of the volatile component. Our results offer promising advantages in manufacturing technologies which involve newly creating interfaces, such as spraying, coating technologies, ink-jet printing, microfluidics, laundry, and stabilization of emulsions in cosmetic and food industry, as well as in geosciences for controlling aerosol formation.

ACS Applied Materials & Interfaces published new progress about Aerosols. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Related Products of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts